SharpED

Make low-resolution maps interpretable

SharpED is a machine-learning tool for reconstructing blurred crystallographic electron-density maps, restoring structural details and improving their interpretability.

Electron density map reconstruction

Discover the method

SharpED transforms low-resolution electron density maps into clear, interpretable maps with atomic-level detail.

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Try online tool

Easy online platform to upload your map and get sharpened results.

Go to SharpED →

Try Phase Studio

Python application that uses SharpED in structure determination process

Open on GitHub →

SharpED for developers

Simple python examples how upload data and wait for the result

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Meet the team

Jan Rohlíček
Jan Rohlíček
Jiří Zelenka
Jiří Zelenka
Monika Kučeráková
Monika Kučeráková
Zdeněk Buk
Zdeněk Buk